The shiny new Fedora 13 is to be released in a few hours. I've installed its x64 variant since beta. And I've spent a lot of time to make wine work in Fedora. And it actually works with PulseAudio :) So, if you are going to use wine in Fedora 13 x64 here is some info which might be helpful.
Getting the latest wine version
At the time of this writing latest wine version in Fedora repos is 1.1.38, in upstream 1.1.44. The latter is also available if Fedora testing repo. So, you might want to enable that repo while installing wine:
yum --enablerepo=updates-testing install wine
Getting rid of crash on audio tab
x64 build of wine is not perfect yet. It actually crashes on audio tab. So, use 32-bit version to configure wine:
wine32 winecfg
It's actually a good idea to use wine32 instead of wine.
Adding readable wine fonts
Default wine font is hardly readable. You should have sharp eyes and good imagination to understand what is written on wine dialogs :)
Installing corefonts with winetricks should fix it:
yum install cabextract
wget http://www.kegel.com/wine/winetricks
chmod a+x winetricks
./winetricks corefonts
Adding mp3 support
Some games (including Morrowind) require mp3 support. Fedora's wine without mp3 support in contrast to Ubuntu. To enable it you should install a mp3 codec. It is recommended to use l3codecx codec, then rename l3codecx.acm file to winemp3.acm. Alternatively you can grab that file from Windows, if you have one at hand. I had no Windows, so I tried installation approach. I've searched for l3codecx and found a few installators (for Windows, of cause). One of them failed in wine but another one worked. l3codecx.acm file appeared in $HOME/.wine/drive_c/windows/syswow64 folder. Instead of renaming it I just made a symbolic link:
cd .wine/drive_c/windows/syswow64 folder
ln -s l3codecx.acm winemp3.acm
And that's all :)